A primary care Symptoms Clinic for patients with medically unexplained symptoms : pilot randomised trial

Peer reviewedPublisher PD

From Blood to Data: An Ethnographic Account of the Construction of the Generation Scotland Population Genetic Database

This thesis is an examination of a population genetic database as both a social and scientific entity. Science and social science usually operate in a dichotomy this is a synergy of the two. The thesis examines practices and processes, and reveals how the formation of the Generation Scotland assemblage is the producer of multiple disconnections and connections layered in the science, technology, objects, people and places. The story is based on a multi‐sited ethnography that moves from the medical setting of blood sample and data collection, through the practices and processes of the laboratory, to end up in the much more diffuse settings of computer analysis. The blood sample is transformed into digital genetic data, and then connected to diverse other data for research. It traces the transformation and aggregation of heterogeneous elements which will become fixed in the population genetic database through scientific ordering and relationships which will be rendered immutable by the technology. In the processes described here, people’s bodies, and information about them, are explicitly rendered as research ‘resources’. The thesis contributes to the growing knowledge of population genetic databases, and it is a response to calls from social science to understand better the science and technology that are currently changing the shape of the social world. Disconnections and connections are creating a framework of new referents between health and illness, identity and relationships in a way that rearticulates the body and the population

Domain crossing: how much expertise is enough?

In CSCW, how much do we need to know about another domain/culture before we observe, intersect and intervene with designs. What optimally would that other culture need to know about us? Is this a “how long is a piece of string” question, or an inquiry where we can consider a variety of contexts and to explicate best practice. The goal of this panel will be to develop heuristics for such practice

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements